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Developing new mass spectrometry-based proteomics technologies to characterize the roles of protein post-translational modifications (PTMs) in cellular physiology and diseases, discover new biomarkers, and explore new therapeutic approaches.

Neurodegenerative diseases and lysosome ion channels

Neuropharmacology and ion channel pharmacology

1.The neural circuit dysfunction of autistic brain;

2. The comorbidity of epilepsy and autism;

3. Gene therapy of neuropsychiatric disorders.

Carbohydate Chemistry, Carbohydrate drugs

Structural Biology

NMR, membrane protein structure, Anti-virus drug mechanism.

Longevity and relations to neuro-endocrine metabolism regulation.

1. Discovery of natural products with novel structures and potential bioactivities from Chinese herbal medicines or plants,

2. Study on the chemical essence of traditional usages of Traditional Chinese Medicine and folk herbs,

3. Drug discovery based on natural potential pharmaceutical lead compounds from Chinese herbal medicines or plants.

1. Targeted drug delivery and smart drug release systems

2. Immunomodulatory drug delivery systems

3. Advanced and innovative drug formulations