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Dean Guo 果德安

Name:Dean Guo 果德安 Title:Principal Investigator Education:Ph.D Contact Number:0760-85286866 E-mail:daguo@simm.ac.cn Address:SSIP Healthcare and Medicine Demonstration Zone, Zhongshan Tsuihang New District, Guangdong 528400

  • Biography

    Prof. Guo graduated with his Ph.D. degree of pharmacognosy from Beijing Medical University in 1990. He currently serves as director of Research Center for TCM Modernization and National Engineering Research Center of TCM Standardization Technology. His research mainly focuses on the quality control and elaboration of pharmacopoeial standards of Chinese herbal medicines. To date, he has published over 700 peer-reviewed papers, among which 550 are cited in SCI journals with 16000 citations.

  • Research Directions

    1. Phytochemical analysis of Chinese Materia Medica

    2. Quality standard elaboration of Chinese Materia Medica

  • Achievements

    Prof. Guo developed a series of strategies and analytical methods including the “Chemical-Metabolic-Biological Analysis” approach named “Trinity Analysis” for the holistic quality standard elaboration, based on which the quality monographs for TCM pharmacopoeial standards were established including Chinese Pharmacopoeia, United States Pharmacopoeia, and European Pharmacopoeia, etc. He received a number of renowned national and international awards including National Natural Science Award and National Science and Technology Progress Award, American Society of Pharmacognosy Varro Tyler Prize, among others.

  • Publications

    5 selected publications in recent 3 years:

    1. QinHao Jin#, JianQing Zhang#, JinJun Hou#, Min Lei, Chen Liu, Xia Wang, Yong Huang, Shuai Yao, BangYeon Hwang, WanYing Wu*, De-an Guo*. Novel C-17 spirost protostane-type triterpenoids from Alisma plantago-aquatica with anti-inflammatory activity in Caco-2 cells. Acta Pharm Sin B, 2019, 9(4): 809-818.

    2. Jinjun Hou#, Zijia Zhang#, Linlin Zhang, Wenyong Wu, Yong Huang, Zhengwei Jia, Lihong Zhou, Lei Gao, Huali Long, Min Lei, Wanying Wu*, De-an Guo*. Spatial lipidomics of eight edible nuts by desorption electrospray ionization with ion mobility mass spectrometry imaging. Food Chem, 2022, 371: 130893.

    3. Xing Liu#, Jianqing Zhang#, Yun Li, Changliang Yao, Yaling An, Wenlong Wei, Shuai Yao, Lin Yang, Yong Huang, Hua Qu, De-an Guo*, In-depth profiling, nontargeted metabolomic and selective ion monitoring of eight chemical markers for simultaneous identification of different part of Eucommia ulmoides in 12 commercial products by UPLC/Qda. Food Chem, 2022, 393:133346.

    4. Wen-Long Wei#, Hao-Jv Li#, Wen-Zhi Yang, Hua Qu, Zhen-Wei Li, Chang-Liang Yao, Jin-JunHou, Wan-Ying Wu*, De-An Guo*, An integrated strategy for comprehensive characterization of metabolites and metabolic profiles of bufadienolides from Venenum Bufonis in rats. J Pharmaceut Anal, 2022, 12(1): 136-144.

    5. Xiaodie Li#, Changliang Yao#, Yun Li, Zhengming Qian, Wenlong Wei, Jianqing Zhang, Jiayuan Li, Qirui Bi, Wenjia Li, Yajun Cui*, De-an Guo*, Systematic screening and structural characterization of dipeptides using offline 2D LC-LTQ orbitrap MS combined with in-house library searching and diagnostic product ion filtering, Cordyceps sinensis as a case study. J Pharmaceut Anal, 2022, 12(2): 263-269.

Tel:86-760-85286866 Fax:0086-760-85283266 Address:SSIP Healthcare and Medicine Demonstration Zone, Zhongshan Tsuihang New District, Guangdong 528400

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